![Point mutations in the N-terminal domain of transactive response DNA-binding protein 43 kDa (TDP-43) compromise its stability, dimerization, and functions - Journal of Biological Chemistry Point mutations in the N-terminal domain of transactive response DNA-binding protein 43 kDa (TDP-43) compromise its stability, dimerization, and functions - Journal of Biological Chemistry](https://www.jbc.org/cms/asset/347ce641-8ae6-4be3-9650-21180620c726/gr1.jpg)
Point mutations in the N-terminal domain of transactive response DNA-binding protein 43 kDa (TDP-43) compromise its stability, dimerization, and functions - Journal of Biological Chemistry
Truncation of the TAR DNA-binding protein 43 is not a prerequisite for cytoplasmic relocalization, and is suppressed by caspase inhibition and by introduction of the A90V sequence variant | PLOS ONE
![IJMS | Free Full-Text | Transactive Response DNA-Binding Protein (TARDBP/TDP-43) Regulates Cell Permissivity to HIV-1 Infection by Acting on HDAC6 IJMS | Free Full-Text | Transactive Response DNA-Binding Protein (TARDBP/TDP-43) Regulates Cell Permissivity to HIV-1 Infection by Acting on HDAC6](https://www.mdpi.com/ijms/ijms-23-06180/article_deploy/html/images/ijms-23-06180-g001.png)
IJMS | Free Full-Text | Transactive Response DNA-Binding Protein (TARDBP/TDP-43) Regulates Cell Permissivity to HIV-1 Infection by Acting on HDAC6
![Frontiers | To Be or Not To Be…Toxic—Is RNA Association With TDP-43 Complexes Deleterious or Protective in Neurodegeneration? Frontiers | To Be or Not To Be…Toxic—Is RNA Association With TDP-43 Complexes Deleterious or Protective in Neurodegeneration?](https://www.frontiersin.org/files/Articles/500516/fmolb-06-00154-HTML/image_m/fmolb-06-00154-g001.jpg)
Frontiers | To Be or Not To Be…Toxic—Is RNA Association With TDP-43 Complexes Deleterious or Protective in Neurodegeneration?
![Phosphorylated TAR DNA-binding protein-43: Aggregation and antibody-based inhibition - ScienceDirect Phosphorylated TAR DNA-binding protein-43: Aggregation and antibody-based inhibition - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0925443921001678-ga1.jpg)
Phosphorylated TAR DNA-binding protein-43: Aggregation and antibody-based inhibition - ScienceDirect
![Interdomain interactions of the transactive response DNA binding protein 43 kDa (TDP-43) | Semantic Scholar Interdomain interactions of the transactive response DNA binding protein 43 kDa (TDP-43) | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/7d4bbb8777926904dfe2880e0dce2cf6c1f42e9a/17-Figure1-1.png)
Interdomain interactions of the transactive response DNA binding protein 43 kDa (TDP-43) | Semantic Scholar
![Frontiers | Expanding the TDP-43 Proteinopathy Pathway From Neurons to Muscle: Physiological and Pathophysiological Functions Frontiers | Expanding the TDP-43 Proteinopathy Pathway From Neurons to Muscle: Physiological and Pathophysiological Functions](https://www.frontiersin.org/files/Articles/815765/fnins-16-815765-HTML/image_m/fnins-16-815765-g001.jpg)
Frontiers | Expanding the TDP-43 Proteinopathy Pathway From Neurons to Muscle: Physiological and Pathophysiological Functions
![JCI - Virus-mediated delivery of antibody targeting TAR DNA-binding protein-43 mitigates associated neuropathology JCI - Virus-mediated delivery of antibody targeting TAR DNA-binding protein-43 mitigates associated neuropathology](https://dm5migu4zj3pb.cloudfront.net/manuscripts/123000/123931/medium/JCI123931.ga.jpg)
JCI - Virus-mediated delivery of antibody targeting TAR DNA-binding protein-43 mitigates associated neuropathology
![IJMS | Free Full-Text | Transactive Response DNA-Binding Protein (TARDBP/TDP-43) Regulates Cell Permissivity to HIV-1 Infection by Acting on HDAC6 IJMS | Free Full-Text | Transactive Response DNA-Binding Protein (TARDBP/TDP-43) Regulates Cell Permissivity to HIV-1 Infection by Acting on HDAC6](https://www.mdpi.com/ijms/ijms-23-06180/article_deploy/html/images/ijms-23-06180-g005.png)
IJMS | Free Full-Text | Transactive Response DNA-Binding Protein (TARDBP/TDP-43) Regulates Cell Permissivity to HIV-1 Infection by Acting on HDAC6
Small Molecule Targeting TDP-43's RNA Recognition Motifs Reduces Locomotor Defects in a Drosophila Model of Amyotrophic Lateral Sclerosis (ALS) | ACS Chemical Biology
![Strategies in the design and development of (TAR) DNA-binding protein 43 (TDP-43) binding ligands - ScienceDirect Strategies in the design and development of (TAR) DNA-binding protein 43 (TDP-43) binding ligands - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0223523421006024-ga1.jpg)
Strategies in the design and development of (TAR) DNA-binding protein 43 (TDP-43) binding ligands - ScienceDirect
![Knockdown of transactive response DNA‐binding protein (TDP‐43) downregulates histone deacetylase 6 | The EMBO Journal Knockdown of transactive response DNA‐binding protein (TDP‐43) downregulates histone deacetylase 6 | The EMBO Journal](https://www.embopress.org/cms/asset/df44492e-8f58-42db-8ff6-cec696aef506/embj2009324-fig-0002-m.jpg)
Knockdown of transactive response DNA‐binding protein (TDP‐43) downregulates histone deacetylase 6 | The EMBO Journal
![Transactive response DNA-binding protein 43 (TDP-43) regulates alternative splicing of tau exon 10: Implications for the pathogenesis of tauopathies - ScienceDirect Transactive response DNA-binding protein 43 (TDP-43) regulates alternative splicing of tau exon 10: Implications for the pathogenesis of tauopathies - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0021925820395983-gr1.jpg)
Transactive response DNA-binding protein 43 (TDP-43) regulates alternative splicing of tau exon 10: Implications for the pathogenesis of tauopathies - ScienceDirect
![Characterization of the upstream and intron promoters of the gene encoding TAR DNA-binding protein | Scientific Reports Characterization of the upstream and intron promoters of the gene encoding TAR DNA-binding protein | Scientific Reports](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41598-021-88015-y/MediaObjects/41598_2021_88015_Fig1_HTML.png)
Characterization of the upstream and intron promoters of the gene encoding TAR DNA-binding protein | Scientific Reports
![Kaplan-Meier survival analysis of all 84 frontotemporal dementia lobar... | Download Scientific Diagram Kaplan-Meier survival analysis of all 84 frontotemporal dementia lobar... | Download Scientific Diagram](https://www.researchgate.net/publication/305265546/figure/fig1/AS:516009427124224@1500037642862/Kaplan-Meier-survival-analysis-of-all-84-frontotemporal-dementia-lobar-degeneration-with_Q320.jpg)
Kaplan-Meier survival analysis of all 84 frontotemporal dementia lobar... | Download Scientific Diagram
![TDP-43: gumming up neurons through protein–protein and protein–RNA interactions: Trends in Biochemical Sciences TDP-43: gumming up neurons through protein–protein and protein–RNA interactions: Trends in Biochemical Sciences](https://www.cell.com/cms/attachment/2002982458/2011316808/gr1.jpg)
TDP-43: gumming up neurons through protein–protein and protein–RNA interactions: Trends in Biochemical Sciences
![Differential toxicity of TAR DNA‐binding protein 43 isoforms depends on their submitochondrial localization in neuronal cells - Salvatori - 2018 - Journal of Neurochemistry - Wiley Online Library Differential toxicity of TAR DNA‐binding protein 43 isoforms depends on their submitochondrial localization in neuronal cells - Salvatori - 2018 - Journal of Neurochemistry - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/013b631f-4493-48e5-aba0-7f32710d5c7b/jnc14465-fig-0007-m.png)
Differential toxicity of TAR DNA‐binding protein 43 isoforms depends on their submitochondrial localization in neuronal cells - Salvatori - 2018 - Journal of Neurochemistry - Wiley Online Library
![TAR DNA-binding protein 43 (TDP-43) pathology in dentate gyrus (DG) in... | Download Scientific Diagram TAR DNA-binding protein 43 (TDP-43) pathology in dentate gyrus (DG) in... | Download Scientific Diagram](https://www.researchgate.net/publication/260483962/figure/fig1/AS:297097552252937@1447844985112/TAR-DNA-binding-protein-43-TDP-43-pathology-in-dentate-gyrus-DG-in-AD-Subjects.png)
TAR DNA-binding protein 43 (TDP-43) pathology in dentate gyrus (DG) in... | Download Scientific Diagram
![IJMS | Free Full-Text | Transactive Response DNA-Binding Protein (TARDBP/TDP-43) Regulates Cell Permissivity to HIV-1 Infection by Acting on HDAC6 IJMS | Free Full-Text | Transactive Response DNA-Binding Protein (TARDBP/TDP-43) Regulates Cell Permissivity to HIV-1 Infection by Acting on HDAC6](https://www.mdpi.com/ijms/ijms-23-06180/article_deploy/html/images/ijms-23-06180-g004a.png)